Due to the significant societal costs associated with this disorder, dementia prevention is a global public health priority. By locating and addressing modifiable risk factors through individualized or community health interventions, dementia incidence can be decreased. Diet is one such risk factor that can be targeted for dementia risk reduction and prevention. Healthier eating habits, such the Mediterranean diet (MedDiet), have been identified as a key strategy for lowering the risk of dementia in studies.
According to recent studies, better adherence to the MedDiet was linked to slower cognitive aging. However, as the majority of earlier studies were carried out in little cohorts with a small number of dementia cases, more research is necessary.
A balanced diet can help lower a person’s hereditary risk for dementia. Yet, earlier investigations addressed the connections between genes and nutrition.
In order to complete the study, individuals had to be 60 years of age or older, self-identify as British, Irish, or another white person, have accurate genetic and nutritional information, and be included in the UK Biobank project. The Oxford WebQ, a web-based nutritional assessment tool, was used to conduct the dietary assessment.
The MedDiet PYRAMID score and the MedDiet Adherence Screener (MEDAS) score were used to measure MedDiet adherence. The PYRAMID score is a 15-point score that is frequently used in epidemiological investigations, whereas the MEDAS score is a 14-point score that is frequently used in observational studies and trials.
The estimate of the genetic risk of dementia employed polygenic risk scores. Using hospital inpatient records and death registries, cases of incident dementia with all-cause mortality were confirmed. ICD, or the International Classification of Diseases
