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In men and women, obesity has varied effects on the prevalence of diabetes, hypertension, and dyslipidemia

Notwithstanding the health dangers and elevated mortality brought on by the illnesses and ailments that accompany it, obesity is nonetheless on the rise globally (comorbidities). There is a dearth of thorough research into the connection between the severity of obesity and the occurrence of these diseases, despite the fact that obesity’s comorbidities (such as diabetes) are well established.

The research team of Project Professor TAMORI Yoshikazu et al. has shown in this study how the prevalence of the three most frequent comorbidities (diabetes, hypertension, and dyslipidemia) differs between men and women depending on the degree of obesity. An analysis of data from over 11,000 Japanese seniors living in Kobe City revealed that being obese raised a man’s probability of developing all three diseases. Conversely, rising obesity in women markedly raised the hazards of diabetes and hypertension, yet only slightly raised the risk of dyslipidemia.

According to the findings, losing weight can help prevent diabetes, hypertension, and dyslipidemia in men as well as diabetes and hypertension in women. Yet, in order to lower dyslipidemia in women, weight loss alone is insufficient.

This study emphasizes how crucial it is to comprehend precisely how obesity impacts the development of concomitant disorders in various ethnic groups and genders in order to provide patients with more effective counseling and care.

On February 9th, 2023, these findings were initially released in Scientific Reports.

Department of Social/Community Medicine and Health Science, Kobe University Graduate School of Medicine, Division of Creative Health Promotion.Obesity can cause complications in numerous diseases, shortens healthy life expectancy and reduces quality of life. Diabetes, hypertension and dyslipidemia are common obesity-related conditions that cause the arteries to harden (arteriosclerosis), which is linked to the development of life-threatening conditions such as strokes and heart disease.

In particular, people of East Asian ethnicity (including Japanese people) are prone to metabolic disorders even if they are only slightly obese. However, detailed research has yet to be conducted into the exact relationship between the degree of obesity and the extent to which comorbidities occur.

65 is often termed the start of old age in developed countries like Japan. Although it is important to avoid becoming overweight in old age, it is also vital to avoid becoming underweight or too thin as this can lead to sarcopenia and frailty.